Successful treatment of cardiogenic shock with an intraaortic balloon pump following aluminium phosphide poisoning

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Successful treatment of cardiogenic shock with an intraaortic balloon pump following aluminium phosphide poisoning.

Aluminium phosphide (AlP) is a highly toxic pesticide that inhibits cytochrome oxidase c and causes oxidative stress. Death results from refractory cardiogenic shock due to myocardial dysfunction. There is very little information regarding extracorporeal life support in severe AlP poisoning. Although several therapies are available, none are curative. We report on the use of an intra-aortic bal...

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Successful Treatment of Aluminium Phosphide Poisoning: A Case Report

Aluminium phosphide (AlP) is used to kill rodents in grain storage. It produces phosphine gas which is toxic for mitochondria. The exact mechanism of action is unclear, but phosphine is thought to produce toxicity by blocking cytochrome-c oxidase, which inhibits oxidative phosphorylation and result in cell death. This poisoning has a high mortality, and survival is unlikely if more than 1.5 g i...

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Using Intra-Aortic Balloon Pump for Management of Cardiogenic Shock Following Aluminum Phosphide Poisoning; Report of 3 Cases

Introduction Aluminium phosphide (Alp) poisoning mortality rate has been reported as high as 70-100%, and refractory hypotension and cardiogenic shock are the two most common presentations leading to death. Due to lack of specific antidote, all treatments are focused on supportive care and recently, intra-aortic balloon pump (IABP) has been suggested to treat cardiogenic shock resulting from to...

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Intraaortic balloon support for myocardial infarction with cardiogenic shock.

BACKGROUND In current international guidelines, intraaortic balloon counterpulsation is considered to be a class I treatment for cardiogenic shock complicating acute myocardial infarction. However, evidence is based mainly on registry data, and there is a paucity of randomized clinical trials. METHODS In this randomized, prospective, open-label, multicenter trial, we randomly assigned 600 pat...

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successful treatment of aluminium phosphide poisoning: a case report

aluminium phosphide (alp) is used to kill rodents in grain storage. it produces phosphine gas which is toxic for mitochondria. the exact mechanism of action is unclear, but phosphine is thought to produce toxicity by blocking cytochrome-c oxidase, which inhibits oxidative phosphorylation and result in cell death. this poisoning has a high mortality, and survival is unlikely if more than 1.5 g i...

متن کامل

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ژورنال

عنوان ژورنال: Archives of Industrial Hygiene and Toxicology

سال: 2014

ISSN: 0004-1254

DOI: 10.2478/10004-1254-65-2014-2393